Metametrix IgG + Celiac Combination Blood Test

What is Celiac Disease?
It is estimated that more than 2 million people in the United States alone have celiac disease. Celiac disease is an autoimmune response to gluten. Inherited factors make some individuals sensitive to a protein called gliadin, which is a part of the total protein or gluten found in grains such as wheat, rye, and barley. When people with celiac disease ingest gluten, their immune system responds by damaging their intestinal villi – the tiny, fingerlike protrusions lining the small intestine. Villi normally allow nutrients from food to be absorbed through the walls of the small intestine into the bloodstream. Damaged villi can lead to long-term complications from impaired absorption such as malnutrition, anemia, osteoporosis, and miscarriage, among other problems.

Components of the Celiac Test:
IgA human tissue transglutaminase (IgA-tTG): Occurs as an immune response to tissue transglutaminase and is rarely found in individuals without celiac disease.
Serum IgA: Identifying serum IgA deficiencies are important for two reasons. First, IgA deficiencies can lead to false negatives for IgA-tTG. Second, individuals with an IgA deficiency have a 10 - 21 times greater risk of developing celiac disease.
IgA antigliadin antibody (IgA-AGA): This antibody develops against gliadin showing consumption of gluten-containing foods that can propagate the enteropathy of celiac disease.

People with celiac disease experience varied symptoms or no symptoms, but can still develop complications of the disease. The following symptoms may indicate a need for a celiac test:
unexplained iron deficient anemia, fatigue, bone and joint pain, arthritis, bone loss or osteoporosis, depression or anxiety, auto immune, tingling of extremities, seizures, infertility or miscariage, canker sores inside mouth, itchy red rash

CPT Codes: 83516 x 2 - Gliadin IgA I, Anti-Gliadin IgA II, 82784- IgA

What is an IgG4 response?
IgG4 antibodies are associated with non-atopic or "delayed" food reactions that can worsen or contribute to many different health problems. These reactions are considered the most common form of immunologically mediated food intolerance. An IgG4 response to food is actually more common than the IgE response, which causes an immediate reaction. IgG4 acts as a blocking antibody, protecting the individual from potentially fatal IgE reactions. These reactions are more difficult to notice since they can occur hours or even days after consumption of an offending food. In some cases, a person's reaction to a food may occur several days after eating the offending food and the link between the food and their symptoms may not be connected. These "hidden" food allergies are caused by increasing blood levels of IgG4 antibodies in reaction to specific foods.

This test is for 90 foods that may be causing "delayed" food reactions" Dairy/Meat/Poultry: beef, casein, chicken, egg white, egg yolk, milk, pork, turkey Fish: clam, cod, crab, flounder, halibut, mackerel, oyster, salmon, trout, tuna
Fruit: apple, apricot, banana, blueberry, cantaloupe, cranberry, grape, honeydew, lemon, orange, peach, pear, pineapple, strawberry, watermelon
Legumes: beans/string, lentil, navy bean, pea/green, peanut, pinto bean, soybean Misc: asperigillus, black pepper, chocolate, cinnamon, coffee, ginger, malt, tea, vanilla, yeast/baker's, yeast/brewer's Nuts & Seeds: almonds, cashew, coconut, pecan, pistachio, sesame, sunflower, walnut
Vegetables: asparagus, avocado, broccoli, cabbage, carrot, cauliflower, celery, cucumber, garlic, lettuce, mushroom, olive, onion, pepper/green, potato, spinach, sweet potato, tomato, zucchini

Metametrix Innovation in IgG Antibody Testing
New patent-pending IgG4 assay allows our test to show less false positives leading to better patient compliance. First test to quantitate IgG4 Eliminates non-specific binding, lowering false positives without rejecting true positives

CPT Code: 86001 x 90 Allergen Specific IgG quantitative or semiquantitative each allergen.

Test results: Will be emailed to you within 2-3 weeks from the time the blood is received at the lab. A hard copy with a rotation diet will be mailed to you one week later.

Testing and Medication: Use of immuno-suppressrive drugs like cortisone will give false negatives. Please discontinue use of such medications for 60 days prior to testing to allow antibody reactions to be observed. It is not necessary to discontinue use of supplements or oral hormones.

Note: do not reduce or stop any medications without consulting your medical doctor first.

New York Residents: May order this test through our company but may not file for insurance reimbursement.

Insurance Reimbursement: Upon email request we will provide you with a receipt to be used for reimbursement from insurance. We cannot guarantee any reimbursement.

Directions for credit card orders: please order through our secure site

Directions for mail orders: (please write the name of the test in the memo section of your check)
Nutritionally Yours
890-F Atlanta Street, Ste. 253
Roswell, GA 30075

Directions for phone orders: please call our office at 678-382-2913
Email: questions to Alanepndsupport@gmail.com

* We have a practitioner at Nutritionally Yours that can order this test for you.